Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer. [electronic resource]
Producer: 20070208Description: 24-31 p. digitalISSN:- 0899-1987
- Acetylation
- Anticarcinogenic Agents -- pharmacology
- Butyrates -- pharmacology
- Chromatin -- physiology
- CpG Islands
- DNA Methylation -- drug effects
- Deoxycytidine -- analogs & derivatives
- Gene Expression Regulation, Enzymologic -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Silencing
- Glutathione S-Transferase pi -- genetics
- Histone Deacetylase Inhibitors
- Histones -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- Isothiocyanates -- pharmacology
- Male
- Neoplasms, Hormone-Dependent -- drug therapy
- Promoter Regions, Genetic -- genetics
- Prostatic Neoplasms -- drug therapy
- Transcription, Genetic
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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