Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. [electronic resource]
Producer: 20061005Description: 50-5 p. digitalISSN:- 1476-4687
- Acetylation
- Alanine -- genetics
- Alanine-tRNA Ligase -- chemistry
- Animals
- Catalysis
- Escherichia coli -- genetics
- Fibroblasts
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Models, Molecular
- Molecular Sequence Data
- Mutation -- genetics
- Neurodegenerative Diseases -- enzymology
- Phenotype
- Protein Folding
- Protein Structure, Tertiary
- Purkinje Cells -- metabolism
- RNA, Transfer, Ala -- genetics
- Serine -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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