Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. [electronic resource]
Producer: 20060929Description: 159-70 p. digitalISSN:- 1535-6108
- Animals
- Capillary Permeability
- Cells, Cultured
- Edema -- metabolism
- Endothelial Cells -- drug effects
- Endothelium, Vascular -- drug effects
- Humans
- Mice
- Mice, Transgenic
- Neoplasms -- blood supply
- Neovascularization, Pathologic -- metabolism
- Proto-Oncogene Proteins c-akt -- genetics
- Rats
- Signal Transduction
- Sirolimus -- pharmacology
- Vascular Endothelial Growth Factor A -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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