Blockade of PARP activity attenuates poly(ADP-ribosyl)ation but offers only partial neuroprotection against NMDA-induced cell death in the rat retina. [electronic resource]
Producer: 20061107Description: 1732-45 p. digitalISSN:- 0022-3042
- Adenosine Triphosphate -- antagonists & inhibitors
- Animals
- Apoptosis
- Cell Death -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Down-Regulation
- Excitatory Amino Acid Agonists -- administration & dosage
- Fluorescent Dyes
- In Situ Nick-End Labeling
- Male
- N-Methylaspartate -- administration & dosage
- Neuroprotective Agents -- pharmacology
- Phenanthrenes -- pharmacology
- Poly Adenosine Diphosphate Ribose -- antagonists & inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors
- Rats
- Rats, Sprague-Dawley
- Retina -- drug effects
- Retinal Ganglion Cells -- cytology
- Stilbamidines
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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