Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP. [electronic resource]
Producer: 20061128Description: 235-44 p. digitalISSN:- 1470-8728
- Animals
- Breast Neoplasms -- enzymology
- COS Cells
- Cell Line, Tumor
- Cell Survival -- physiology
- Chlorocebus aethiops
- Down-Regulation
- Endoplasmic Reticulum -- enzymology
- Fibroblasts -- enzymology
- Humans
- Immediate-Early Proteins -- metabolism
- Mice
- Mice, Knockout
- Proteasome Endopeptidase Complex -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
- Transfection
- Ubiquitin -- metabolism
- Ubiquitin-Protein Ligases -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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