Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53. [electronic resource]
Producer: 20070105Description: F1300-7 p. digitalISSN:- 1931-857X
- Animals
- Antineoplastic Agents -- toxicity
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins
- Caspase 1 -- metabolism
- Caspase 3 -- genetics
- Caspase Inhibitors
- Cell Cycle Proteins -- genetics
- Cisplatin -- toxicity
- DNA-Binding Proteins -- genetics
- Enzyme Inhibitors -- pharmacology
- Gene Expression
- HeLa Cells
- Humans
- Kidney Tubules, Proximal -- drug effects
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- genetics
- Rats
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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