Nucleoside reverse transcriptase inhibitors prevent HIV protease inhibitor-induced atherosclerosis by ubiquitination and degradation of protein kinase C. [electronic resource]
Producer: 20070215Description: C1271-8 p. digitalISSN:- 0363-6143
- Animals
- Antioxidants -- administration & dosage
- Atherosclerosis -- chemically induced
- CD36 Antigens -- metabolism
- Cholesterol -- metabolism
- Didanosine -- metabolism
- Enzyme Activation
- HIV Infections -- drug therapy
- HIV Protease Inhibitors -- adverse effects
- Humans
- Macrophages -- metabolism
- Mice
- Mice, Knockout
- Protein Kinase C-alpha -- antagonists & inhibitors
- Receptors, LDL -- genetics
- Reverse Transcriptase Inhibitors -- metabolism
- Ritonavir -- adverse effects
- Stavudine -- metabolism
- Ubiquitin -- metabolism
- alpha-Tocopherol -- administration & dosage
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Retracted Publication
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