The calpain inhibitor MDL-28170 and the AMPA/KA receptor antagonist CNQX inhibit neurofilament degradation and enhance neuronal survival in kainic acid-treated hippocampal slice cultures. [electronic resource]
Producer: 20060804Description: 2686-94 p. digitalISSN:- 0953-816X
- 6-Cyano-7-nitroquinoxaline-2,3-dione -- pharmacology
- Animals
- Blotting, Western
- Calpain -- antagonists & inhibitors
- Cell Death -- drug effects
- Cysteine Proteinase Inhibitors -- pharmacology
- Dipeptides -- pharmacology
- Electrophoresis, Polyacrylamide Gel
- Excitatory Amino Acid Antagonists -- pharmacology
- Hippocampus -- drug effects
- Immunohistochemistry
- Kainic Acid -- pharmacology
- Microscopy, Confocal
- Neurofilament Proteins -- drug effects
- Neurons -- drug effects
- Organ Culture Techniques
- Rats
- Rats, Sprague-Dawley
- Receptors, AMPA -- antagonists & inhibitors
- Receptors, Kainic Acid -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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