Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich disease fibroblasts. [electronic resource]
Producer: 20061113Description: 351-60 p. digitalISSN:- 1525-0016
- Adult
- Cells, Cultured
- Codon, Nonsense
- Collagen Type VI -- analysis
- Fibroblasts -- chemistry
- Genetic Vectors -- genetics
- Humans
- Male
- Muscular Dystrophies -- genetics
- Mutation
- Phenotype
- Phosphatidylinositol 3-Kinases -- genetics
- Phosphoinositide-3 Kinase Inhibitors
- Plasmids -- genetics
- Protein Serine-Threonine Kinases
- RNA Helicases
- RNA Interference
- RNA Stability
- RNA, Messenger -- metabolism
- RNA, Small Interfering -- genetics
- Trans-Activators -- antagonists & inhibitors
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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