Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. [electronic resource]
Producer: 20060816Description: 258-66 p. digitalISSN:- 0022-3042
- Analysis of Variance
- Animals
- Caspases -- metabolism
- Cell Death -- drug effects
- Cells, Cultured
- Cerebral Cortex -- cytology
- Coculture Techniques -- methods
- Dose-Response Relationship, Drug
- Drug Interactions
- Embryo, Mammalian
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Excitatory Amino Acid Agonists -- pharmacology
- Free Radicals -- metabolism
- Immunohistochemistry -- methods
- Interleukin-1 -- toxicity
- N-Methylaspartate -- pharmacology
- Nerve Tissue Proteins -- metabolism
- Neuroglia -- physiology
- Neurons -- drug effects
- Rats
- Rats, Sprague-Dawley
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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