TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology. [electronic resource]
Producer: 20060816Description: 10444-10449 p. digitalISSN:- 0027-8424
- Animals
- Brain-Derived Neurotrophic Factor -- pharmacology
- Cell Membrane -- drug effects
- Cell Shape
- Cells, Cultured
- Chlorocebus aethiops
- Guanine Nucleotide Exchange Factors -- genetics
- Neoplasm Proteins -- genetics
- Neurites -- drug effects
- Neurons -- cytology
- Phosphotyrosine -- metabolism
- Protein Binding
- Pseudopodia -- drug effects
- Rats
- Rats, Sprague-Dawley
- Receptor, trkB -- metabolism
- T-Lymphoma Invasion and Metastasis-inducing Protein 1
- rac1 GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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