The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. [electronic resource]
Producer: 20060911Description: 3012-23 p. digitalISSN:- 0261-4189
- Arrestins -- metabolism
- Cell Line
- Dimerization
- Down-Regulation
- Humans
- Ligands
- Melatonin -- metabolism
- Mutation
- Nerve Tissue Proteins -- biosynthesis
- Protein Binding
- Receptor, Melatonin, MT1 -- antagonists & inhibitors
- Receptor, Melatonin, MT2 -- antagonists & inhibitors
- Receptors, G-Protein-Coupled -- biosynthesis
- Recombinant Fusion Proteins -- genetics
- Signal Transduction
- beta-Arrestins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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