Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling. [electronic resource]
Producer: 20061016Description: 21710-21719 p. digitalISSN:- 0021-9258
- Animals
- Benzoquinones -- pharmacology
- COS Cells
- Cell Movement
- Cell Proliferation
- Chlorocebus aethiops
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Lactams, Macrocyclic -- pharmacology
- Mice
- Mutation, Missense
- NIH 3T3 Cells
- Neoplasms
- Proto-Oncogene Proteins c-cbl
- Receptor Protein-Tyrosine Kinases -- genetics
- Signal Transduction -- drug effects
- Ubiquitin-Protein Ligases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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