Peptides based on alphaV-binding domains of erythrocyte ICAM-4 inhibit sickle red cell-endothelial interactions and vaso-occlusion in the microcirculation. [electronic resource]
Producer: 20061124Description: C922-30 p. digitalISSN:- 0363-6143
- Anemia, Sickle Cell -- pathology
- Animals
- Cell Adhesion -- drug effects
- Cell Adhesion Molecules -- chemistry
- Endothelial Cells -- cytology
- Erythrocytes, Abnormal -- drug effects
- Humans
- In Vitro Techniques
- Integrin alphaV -- metabolism
- Microcirculation -- drug effects
- Peptides -- chemistry
- Platelet Activating Factor -- pharmacology
- Protein Binding -- drug effects
- Protein Structure, Tertiary
- Protein Transport -- drug effects
- Rats
- Regression Analysis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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