The BRCA1 COOH-terminal region acts as an RNA polymerase II carboxyl-terminal domain kinase inhibitor that modulates p21WAF1/CIP1 expression. [electronic resource]
Producer: 20060918Description: 21119-21130 p. digitalISSN:- 0021-9258
- BRCA1 Protein -- chemistry
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Cyclin-Dependent Kinase Inhibitor p21 -- chemistry
- DNA Damage
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation
- HeLa Cells
- Humans
- Phosphorylation
- Positive Transcriptional Elongation Factor B -- chemistry
- Protein Structure, Tertiary
- RNA Polymerase II -- chemistry
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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