Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations. [electronic resource]
Producer: 20061213Description: 7086-95 p. digitalISSN:- 0950-9232
- Alanine -- genetics
- Amino Acid Sequence
- Animals
- Cell Membrane -- metabolism
- Cysteine -- genetics
- Dimerization
- Disulfides -- metabolism
- Drosophila Proteins -- chemistry
- Drosophila melanogaster
- Gene Expression -- drug effects
- Glial Cell Line-Derived Neurotrophic Factor -- pharmacology
- Humans
- Molecular Sequence Data
- Multiple Endocrine Neoplasia Type 2a -- genetics
- Mutation -- genetics
- Protein Binding
- Proto-Oncogene Proteins c-ret -- chemistry
- Sequence Alignment
- Sequence Homology, Amino Acid
- Thyroid Neoplasms -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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