Evaluation of glutathione S-transferase polymorphisms and mutagen sensitivity as risk factors for the development of second primary tumors in patients previously diagnosed with early-stage head and neck cancer. [electronic resource]
Producer: 20060718Description: 2636-44 p. digitalISSN:- 0008-543X
- Aged
- Alcohol Drinking -- adverse effects
- Bleomycin -- toxicity
- Carcinoma, Squamous Cell -- genetics
- Chemoprevention -- methods
- Chromosome Breakage
- Disease-Free Survival
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Predisposition to Disease
- Genotype
- Glutathione Transferase -- genetics
- Head and Neck Neoplasms -- genetics
- Humans
- Isotretinoin -- therapeutic use
- Male
- Middle Aged
- Mutagens -- toxicity
- Neoplasms, Second Primary -- etiology
- Odds Ratio
- Polymorphism, Genetic
- Proportional Hazards Models
- Risk Factors
- Smoking -- adverse effects
- Time Factors
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
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