Determining the structural basis for specificity of ligands using crystallographic screening. [electronic resource]
Producer: 20060824Description: 405-11 p. digitalISSN:- 1085-9195
- Binding Sites -- drug effects
- Computer Simulation
- Crystallization -- methods
- Crystallography, X-Ray -- methods
- Enzyme Inhibitors -- chemistry
- Ligands
- Models, Molecular
- Phosphates -- chemistry
- Protein Binding -- drug effects
- Protein Folding
- Purine Nucleosides
- Purine-Nucleoside Phosphorylase -- antagonists & inhibitors
- Structure-Activity Relationship
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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