Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing. [electronic resource]
Producer: 20060609Description: 3728-37 p. digitalISSN:- 0270-7306
- Animals
- Azacitidine -- analogs & derivatives
- Blotting, Western
- Carcinoma -- pathology
- Cell Line
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chromatin Immunoprecipitation
- DNA Methylation -- drug effects
- Decitabine
- Dose-Response Relationship, Drug
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors -- pharmacology
- Epigenesis, Genetic
- Fibroblasts -- cytology
- Gene Silencing -- drug effects
- Histones -- chemistry
- Humans
- Kinetics
- Lung Neoplasms -- pathology
- Lysine -- chemistry
- Methyltransferases -- metabolism
- Mice
- Nickel -- pharmacology
- Trace Elements -- pharmacology
- Transgenes -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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