Pharmacodynamics of levofloxacin against Pseudomonas aeruginosa with reduced susceptibility due to different efflux pumps: do elevated MICs always predict reduced in vivo efficacy? [electronic resource]
Producer: 20060609Description: 1628-32 p. digitalISSN:- 0066-4804
- Animals
- Anti-Bacterial Agents -- blood
- Area Under Curve
- Bacterial Outer Membrane Proteins -- genetics
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Resistance, Bacterial
- Gene Deletion
- Genes, Bacterial
- Levofloxacin
- Male
- Membrane Proteins
- Membrane Transport Proteins
- Mice
- Microbial Sensitivity Tests
- Neutropenia -- microbiology
- Ofloxacin -- blood
- Pseudomonas aeruginosa -- drug effects
- Sepsis -- microbiology
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Publication Type: Journal Article
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