Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model. [electronic resource]
Producer: 20060531Description: 153-65 p. digitalISSN:- 1474-9718
- Amyloid beta-Protein Precursor -- genetics
- Amyotrophic Lateral Sclerosis -- enzymology
- Animals
- Cell Survival
- Copper -- metabolism
- Disease Models, Animal
- Gene Expression
- Glial Fibrillary Acidic Protein -- metabolism
- Gliosis -- pathology
- Mice
- Mice, Inbred C57BL
- Mice, Neurologic Mutants
- Mice, Transgenic
- Movement -- physiology
- Oxidative Stress
- Protein Structure, Quaternary
- Spinal Cord -- cytology
- Superoxide Dismutase -- chemistry
- Superoxide Dismutase-1
- Zinc -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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