Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22. [electronic resource]
Producer: 20060810Description: 1369-80 p. digitalISSN:- 0741-5400
- Acetophenones -- pharmacology
- Benzopyrans -- pharmacology
- Calcium -- physiology
- Calcium Channels -- physiology
- Calcium Signaling -- drug effects
- Catalytic Domain
- Cell Line, Tumor -- cytology
- Chemokine CCL17
- Chemokine CCL22
- Chemokines, CC -- genetics
- Chemotaxis -- drug effects
- Chromones -- pharmacology
- Diglycerides -- physiology
- Estrenes -- pharmacology
- Humans
- Indoles -- pharmacology
- Inositol 1,4,5-Trisphosphate -- physiology
- Inositol 1,4,5-Trisphosphate Receptors
- Leukemia-Lymphoma, Adult T-Cell -- pathology
- Morpholines -- pharmacology
- Pertussis Toxin -- pharmacology
- Phosphatidylinositol 3-Kinases -- physiology
- Phosphatidylinositol Diacylglycerol-Lyase -- antagonists & inhibitors
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Phosphothreonine -- chemistry
- Protein Processing, Post-Translational -- drug effects
- Pyrroles -- pharmacology
- Pyrrolidinones -- pharmacology
- Receptors, CCR4
- Receptors, Chemokine -- physiology
- Receptors, Cytoplasmic and Nuclear -- antagonists & inhibitors
- Recombinant Fusion Proteins -- pharmacology
- T-Lymphocytes -- cytology
- Th2 Cells -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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