Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence. [electronic resource]
Producer: 20060614Description: 1741-52 p. digitalISSN:- 0261-4189
- Anaphase-Promoting Complex-Cyclosome
- Animals
- Cell Cycle -- physiology
- Cell Line
- Cell Transformation, Viral
- Cellular Senescence -- physiology
- Cyclin A -- metabolism
- Cyclin B -- metabolism
- Cyclin B1
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p27 -- metabolism
- Enzyme Activation
- Gene Products, tax -- genetics
- Humans
- Mice
- Neoplasm Proteins -- metabolism
- Polyubiquitin -- metabolism
- S-Phase Kinase-Associated Proteins -- metabolism
- Securin
- Tumor Suppressor Protein p53 -- physiology
- Ubiquitin-Protein Ligase Complexes -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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