Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme. [electronic resource]
Producer: 20060818Description: 853-61 p. digitalISSN:- 0961-8368
- Amino Acid Sequence
- Bacteriophage T4 -- chemistry
- Crystallography, X-Ray
- Dose-Response Relationship, Drug
- Evolution, Molecular
- Guanidine -- chemistry
- Kinetics
- Ligands
- Magnetic Resonance Spectroscopy
- Methylguanidine -- metabolism
- Models, Molecular
- Molecular Sequence Data
- Muramidase -- chemistry
- Protein Binding
- Protein Conformation -- drug effects
- Solutions -- chemistry
- Thermodynamics
- Tryptophan -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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