Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines. [electronic resource]
Producer: 20061024Description: 60-70 p. digitalISSN:- 0026-895X
- Antineoplastic Agents, Phytogenic -- metabolism
- Apoptosis -- drug effects
- Binding Sites
- Binding, Competitive
- Blotting, Western
- CDC2 Protein Kinase -- metabolism
- Carbamates -- pharmacology
- Cell Division
- Cell Line, Tumor
- Colchicine -- metabolism
- Cyclin B -- metabolism
- Cyclin B1
- Dose-Response Relationship, Drug
- G2 Phase
- Humans
- K562 Cells
- Metaphase -- drug effects
- Microtubules -- drug effects
- Oxazepines -- metabolism
- Pyrroles -- metabolism
- Time Factors
- Tubulin -- metabolism
- Vinblastine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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