The phenotypic differentiation of locus ceruleus noradrenergic neurons mediated by brain-derived neurotrophic factor is enhanced by corticotropin releasing factor through the activation of a cAMP-dependent signaling pathway. [electronic resource]
Producer: 20061024Description: 30-40 p. digitalISSN:- 0026-895X
- Animals
- Blotting, Western
- Brain-Derived Neurotrophic Factor -- pharmacology
- Cell Differentiation -- drug effects
- Cells, Cultured
- Corticotropin-Releasing Hormone -- pharmacology
- Cyclic AMP -- metabolism
- Dose-Response Relationship, Drug
- Drug Synergism
- Enzyme Activation -- drug effects
- Gene Expression -- drug effects
- Locus Coeruleus -- cytology
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Neurons -- cytology
- Norepinephrine -- metabolism
- Norepinephrine Plasma Membrane Transport Proteins -- genetics
- Rats
- Rats, Wistar
- Receptor, trkB -- genetics
- Receptors, Corticotropin-Releasing Hormone -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Tyrosine 3-Monooxygenase -- genetics
- CRF Receptor, Type 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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