The -318 C>G single-nucleotide polymorphism in GNAI2 gene promoter region impairs transcriptional activity through specific binding of Sp1 transcription factor and is associated with high blood pressure in Caucasians from Italy. [electronic resource]
Producer: 20070112Description: S115-9 p. digitalISSN:- 1046-6673
- Adult
- Alleles
- Cell Line
- Female
- GTP-Binding Protein alpha Subunit, Gi2 -- genetics
- Genetic Variation
- HeLa Cells
- Humans
- Hypertension -- genetics
- Insulin Resistance -- genetics
- Italy
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- Risk
- Sp1 Transcription Factor -- metabolism
- Transcription, Genetic
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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