The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library: application to a lead optimization of a human A3 adenosine receptor antagonist. [electronic resource]
Producer: 20061017Description: 4923-32 p. digitalISSN:- 0968-0896
- Adenosine A3 Receptor Antagonists
- Binding Sites
- Combinatorial Chemistry Techniques
- Drug Design
- Humans
- In Vitro Techniques
- Least-Squares Analysis
- Models, Molecular
- Protein Conformation
- Pyrimidines -- chemical synthesis
- Quantitative Structure-Activity Relationship
- Receptor, Adenosine A3 -- chemistry
- Static Electricity
- User-Computer Interface
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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