Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors). [electronic resource]
Producer: 20070405Description: 242-51 p. digitalISSN:- 0304-3835
- Animals
- Antineoplastic Agents -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Depsipeptides -- administration & dosage
- Dose-Response Relationship, Drug
- Drug Synergism
- Enzyme Inhibitors -- administration & dosage
- Humans
- Mammary Neoplasms, Experimental -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Molecular Structure
- Neurofibromin 1 -- deficiency
- Nitriles -- administration & dosage
- Pancreatic Neoplasms -- drug therapy
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Pyrazoles -- administration & dosage
- Pyrimidines -- administration & dosage
- Quaternary Ammonium Compounds -- administration & dosage
- Signal Transduction -- drug effects
- Time Factors
- Treatment Outcome
- Xenograft Model Antitumor Assays -- methods
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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