Caspase cleaved presenilin-1 is part of active gamma-secretase complexes. [electronic resource]
Producer: 20060608Description: 356-64 p. digitalISSN:- 0022-3042
- Amyloid Precursor Protein Secretases
- Amyloid beta-Protein Precursor -- genetics
- Apoptosis -- drug effects
- Aspartic Acid Endopeptidases
- Blotting, Western -- methods
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chromatin -- metabolism
- Endopeptidases -- metabolism
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Humans
- Immunoprecipitation -- methods
- Luciferases -- biosynthesis
- Membrane Proteins -- metabolism
- Multiprotein Complexes -- metabolism
- Mutation
- Neuroblastoma
- Peptide Fragments
- Presenilin-1
- Protein Structure, Tertiary
- Staurosporine -- pharmacology
- Subcellular Fractions -- drug effects
- Tetrazolium Salts
- Thiazoles
- Transfection -- methods
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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