Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors. [electronic resource]
Producer: 20060428Description: 1855-66 p. digitalISSN:- 0022-2623
- Administration, Oral
- Animals
- Anti-Anxiety Agents -- adverse effects
- Anticonvulsants -- adverse effects
- Binding Sites
- Brain -- drug effects
- GABA Antagonists
- GABA-A Receptor Agonists
- Imidazoles -- adverse effects
- Male
- Mice
- Models, Molecular
- Morpholines -- adverse effects
- Pentylenetetrazole
- Piperidines -- adverse effects
- Pyrroles -- adverse effects
- Quantitative Structure-Activity Relationship
- Radioligand Assay
- Rats
- Rats, Wistar
- Rotarod Performance Test
- Seizures -- chemically induced
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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