Hepatotoxicity profile of single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia, its impact on clinical outcome and the effect of genetic polymorphisms on the incidence of hepatotoxicity. [electronic resource]
Producer: 20060912Description: 881-3 p. digitalISSN:- 0887-6924
- Adult
- Arsenic Trioxide
- Arsenicals -- administration & dosage
- Chemical and Drug Induced Liver Injury -- complications
- Cohort Studies
- Disease-Free Survival
- Female
- Follow-Up Studies
- Genetic Predisposition to Disease
- Humans
- Incidence
- Leukemia, Promyelocytic, Acute -- diagnosis
- Liver -- drug effects
- Liver Function Tests
- Male
- Methylenetetrahydrofolate Reductase (NADPH2) -- genetics
- Oxides -- administration & dosage
- Polymorphism, Genetic
- Remission Induction
- Risk Factors
- Survival Rate
- Treatment Outcome
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Publication Type: Clinical Trial; Letter
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