Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies. [electronic resource]
Producer: 20060417Description: 1251-9 p. digitalISSN:- 1078-0432
- Abdominal Pain -- etiology
- Adult
- Aged
- Blotting, Western
- Combined Modality Therapy -- adverse effects
- Diarrhea -- etiology
- Dose-Response Relationship, Drug
- Female
- Fever -- etiology
- Gene Expression -- drug effects
- Humans
- Infusions, Intravenous
- Leukocytes, Mononuclear -- drug effects
- Male
- Middle Aged
- Neoplasms -- drug therapy
- Oligodeoxyribonucleotides -- administration & dosage
- Pharyngitis -- etiology
- Proto-Oncogene Proteins c-raf -- blood
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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