Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles. [electronic resource]
Producer: 20060329Description: 995-1005 p. digitalISSN:- 0022-2623
- Antiviral Agents -- chemical synthesis
- Biological Availability
- Crystallography, X-Ray
- Cyclization
- Hepacivirus -- drug effects
- Humans
- Leukocyte Elastase -- antagonists & inhibitors
- Macrocyclic Compounds -- chemical synthesis
- Models, Molecular
- Oligopeptides -- chemical synthesis
- Proline -- analogs & derivatives
- Serine Endopeptidases -- chemistry
- Serine Proteinase Inhibitors -- chemical synthesis
- Stereoisomerism
- Structure-Activity Relationship
- Viral Nonstructural Proteins -- antagonists & inhibitors
- Virus Replication
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Publication Type: Journal Article
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