Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron. [electronic resource]
Producer: 20060403Description: 1333-46 p. digitalISSN:- 0270-7306
- Alternative Splicing
- Animals
- Base Sequence
- Cell Line
- Cyclic AMP Response Element-Binding Protein -- genetics
- DNA -- genetics
- Exons
- Humans
- Introns
- Mice
- Models, Genetic
- Molecular Sequence Data
- Muscular Atrophy, Spinal -- genetics
- Nerve Tissue Proteins -- genetics
- Oligoribonucleotides, Antisense -- genetics
- RNA Splicing
- RNA-Binding Proteins -- genetics
- SMN Complex Proteins
- Sequence Deletion
- Sequence Homology, Nucleic Acid
- Silencer Elements, Transcriptional
- Survival of Motor Neuron 1 Protein
- Survival of Motor Neuron 2 Protein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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