Application of HSVtk suicide gene to X-SCID gene therapy: ganciclovir treatment offsets gene corrected X-SCID B cells. [electronic resource]
Producer: 20060418Description: 391-8 p. digitalISSN:- 0006-291X
- Antiviral Agents -- pharmacology
- B-Lymphocytes -- immunology
- Cell Line
- Cell Line, Transformed
- Cell Proliferation
- Cell Survival
- DNA, Complementary -- metabolism
- Electrophoresis, Polyacrylamide Gel
- Flow Cytometry
- Ganciclovir -- pharmacology
- Genetic Therapy -- methods
- Genetic Vectors
- Humans
- Interleukin-2 -- metabolism
- Janus Kinase 3
- Leukocytes, Mononuclear -- metabolism
- Models, Genetic
- Mutagenesis
- Mutation
- Phosphorylation
- Protein-Tyrosine Kinases -- metabolism
- Retroviridae
- Severe Combined Immunodeficiency -- genetics
- Simplexvirus -- enzymology
- Thymidine Kinase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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