The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections. [electronic resource]
Producer: 20060907Description: 596-606 p. digitalISSN:- 0007-1188
- Animals
- Autoradiography
- Brain -- drug effects
- Drug Contamination
- Enzyme Activation
- GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
- Guanosine 5'-O-(3-Thiotriphosphate)
- Histamine Release
- Hydrogen-Ion Concentration
- Isoxazoles -- pharmacology
- Male
- Mast Cells -- drug effects
- Phospholipase D -- metabolism
- Propionates -- pharmacology
- Rats
- Receptor, Serotonin, 5-HT1A -- drug effects
- Receptors, Lysophosphatidic Acid -- antagonists & inhibitors
- Signal Transduction
- Sulfur Radioisotopes
- p-Methoxy-N-methylphenethylamine -- chemistry
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Publication Type: Journal Article
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