Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia. [electronic resource]
Producer: 20060208Description: 23-34 p. digitalISSN:- 0009-9236
- Adult
- Anticoagulants
- Antithrombins -- pharmacokinetics
- Biomarkers
- Blood Coagulation -- drug effects
- Dose-Response Relationship, Drug
- Double-Blind Method
- Endotoxemia -- chemically induced
- Fibrinolysis -- drug effects
- Hemodynamics -- drug effects
- Humans
- In Vitro Techniques
- Inflammation Mediators -- blood
- Interleukin-6 -- metabolism
- Leukocyte Count
- Lipopolysaccharides -- pharmacology
- Male
- Partial Thromboplastin Time
- Peptide Fragments -- analysis
- Prothrombin -- analysis
- Prothrombin Time
- RNA, Messenger -- biosynthesis
- Recombinant Proteins -- pharmacokinetics
- Thrombelastography
- Thrombin -- biosynthesis
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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