Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function. [electronic resource]
Producer: 20060223Description: 69-77 p. digitalISSN:- 0008-5472
- Amino Acid Sequence
- Chromosome Segregation
- Chromosomes, Human, Pair 8 -- genetics
- DNA, Neoplasm -- genetics
- DNA-Binding Proteins -- genetics
- Genetic Linkage
- Genetic Predisposition to Disease
- Germ-Line Mutation
- Homeodomain Proteins -- genetics
- Humans
- Male
- Middle Aged
- Models, Molecular
- Molecular Sequence Data
- Nuclear Magnetic Resonance, Biomolecular
- Prostatic Neoplasms -- genetics
- Protein Structure, Tertiary
- RNA, Messenger -- genetics
- Structure-Activity Relationship
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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