Caspase activation and apoptosis induction by adalimumab: demonstration in vitro and in vivo in a chimeric mouse model. [electronic resource]
Producer: 20060328Description: 22-8 p. digitalISSN:- 1078-0998
- Adalimumab
- Amino Acid Chloromethyl Ketones -- pharmacology
- Animals
- Antibodies, Monoclonal -- metabolism
- Antibodies, Monoclonal, Humanized
- Apoptosis -- drug effects
- Caspase 3
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Line
- Chimera
- Cysteine Proteinase Inhibitors -- pharmacology
- Enzyme Precursors
- Female
- Humans
- Mice
- Mice, Inbred Strains
- Mice, SCID
- Monocytes -- metabolism
- Tumor Necrosis Factor-alpha -- immunology
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Publication Type: Journal Article
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