The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells. [electronic resource]
Producer: 20060504Description: 4624-37 p. digitalISSN:- 0021-9258
- 2',5'-Oligoadenylate Synthetase -- physiology
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Antiviral Agents -- pharmacology
- Base Sequence
- Blotting, Southern
- Blotting, Western
- Cell Line
- Cell Survival
- Culicidae -- virology
- DNA Primers -- chemistry
- Endoribonucleases -- chemistry
- Fibroblasts -- metabolism
- Fluorescent Antibody Technique, Indirect
- Immunity
- Immunoprecipitation
- Interferons -- metabolism
- Mice
- Molecular Sequence Data
- Protease Inhibitors -- pharmacology
- Proteasome Endopeptidase Complex -- metabolism
- RNA, Viral -- chemistry
- Reverse Transcriptase Polymerase Chain Reaction
- Sensitivity and Specificity
- Tetrazolium Salts -- pharmacology
- Thiazoles -- pharmacology
- Transfection
- Virus Replication
- West Nile Fever -- pathology
- West Nile virus -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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