IL-12 + GM-CSF microsphere therapy induces eradication of advanced spontaneous tumors in her-2/neu transgenic mice but fails to achieve long-term cure due to the inability to maintain effector T-cell activity. [electronic resource]
Producer: 20060201Description: 10-20 p. digitalISSN:- 1524-9557
- Adoptive Transfer
- Animals
- Enzyme-Linked Immunosorbent Assay
- Female
- Granulocyte-Macrophage Colony-Stimulating Factor -- administration & dosage
- Immunohistochemistry
- Interferon-gamma -- blood
- Interleukin-12 -- administration & dosage
- Mammary Neoplasms, Experimental -- drug therapy
- Mice
- Mice, Transgenic
- Microspheres
- Receptor, ErbB-2 -- genetics
- T-Lymphocytes -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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