Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation. [electronic resource]
Producer: 20060222Description: 98-107 p. digitalISSN:- 1524-4539
- Animals
- Apolipoproteins E -- deficiency
- Atherosclerosis -- etiology
- CD36 Antigens -- physiology
- Cathepsin K
- Cathepsins -- deficiency
- Cell Size
- Cells, Cultured
- Collagen -- analysis
- Disease Progression
- Fibrosis -- etiology
- Foam Cells -- pathology
- Lipoproteins, LDL -- metabolism
- Macrophages -- pathology
- Mice
- Mice, Knockout
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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