NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity. [electronic resource]
Producer: 20060221Description: 3754-62 p. digitalISSN:- 1524-4539
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Adolescent
- Adult
- Aged
- Animals
- Anthracyclines -- metabolism
- Biological Transport -- genetics
- Case-Control Studies
- Doxorubicin -- metabolism
- Drug-Related Side Effects and Adverse Reactions -- genetics
- Female
- Free Radicals -- metabolism
- Heart Diseases -- chemically induced
- Humans
- Male
- Membrane Glycoproteins -- genetics
- Mice
- Mice, Knockout
- Middle Aged
- NADPH Oxidase 2
- NADPH Oxidases -- genetics
- Pharmacogenetics -- methods
- Polymorphism, Genetic
- Ventricular Function, Left -- drug effects
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Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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