Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease. [electronic resource]
Producer: 20060207Description: 2755-64 p. digitalISSN:- 0953-816X
- Amphetamine -- pharmacology
- Animals
- Astrocytes -- physiology
- Cell Count
- Cell Transplantation
- Cells, Cultured
- Central Nervous System Stimulants -- pharmacology
- Enzyme-Linked Immunosorbent Assay
- Female
- Genetic Vectors
- Glial Cell Line-Derived Neurotrophic Factor -- genetics
- Immunohistochemistry
- Lentivirus -- genetics
- Nerve Fibers -- physiology
- Oxidopamine
- Parkinson Disease, Secondary -- chemically induced
- Rats
- Rats, Sprague-Dawley
- Stereotyped Behavior -- drug effects
- Substantia Nigra -- cytology
- Sympatholytics
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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