In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent. [electronic resource]
Producer: 20060124Description: 8503-11 p. digitalISSN:- 1078-0432
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- metabolism
- Administration, Oral
- Animals
- Chromatography, High Pressure Liquid
- Cytochrome P-450 Enzyme System -- metabolism
- Drug Therapy, Combination
- HIV Protease Inhibitors -- pharmacology
- Humans
- In Vitro Techniques
- Mass Spectrometry
- Methylurea Compounds -- blood
- Mice
- Microsomes, Liver -- drug effects
- Neoplasm Proteins -- metabolism
- Ritonavir -- pharmacology
- Substrate Specificity
- Tubulin -- metabolism
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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