The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. [electronic resource]
Producer: 19920623Description: 703-13 p. digitalISSN:- 0092-8674
- Amino Acid Sequence
- Animals
- Base Sequence
- Cells, Cultured
- Chlorocebus aethiops
- DNA Mutational Analysis
- DNA-Binding Proteins -- physiology
- Gene Expression Regulation
- HeLa Cells
- Humans
- In Vitro Techniques
- Mifepristone -- pharmacology
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Progesterone -- metabolism
- Receptors, Progesterone -- antagonists & inhibitors
- Recombinant Proteins
- Structure-Activity Relationship
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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