Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases. [electronic resource]
Producer: 20060111Description: 4393-401 p. digitalISSN:- 0146-0404
- ATP-Binding Cassette Transporters -- genetics
- Animals
- Chromatography, Gel
- Chromatography, High Pressure Liquid
- Dark Adaptation -- drug effects
- Dose-Response Relationship, Drug
- Electroretinography
- Fenretinide -- administration & dosage
- Lipofuscin -- metabolism
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Microscopy, Fluorescence
- Photic Stimulation
- Pigment Epithelium of Eye -- metabolism
- Prealbumin -- metabolism
- Pyridinium Compounds -- metabolism
- Retina -- drug effects
- Retinal Degeneration -- blood
- Retinoids -- metabolism
- Retinol-Binding Proteins -- metabolism
- Spectrometry, Fluorescence
- Vitamin A -- blood
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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