Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms. [electronic resource]
Producer: 20060307Description: 2044-52 p. digitalISSN:- 0021-9258
- Anilides -- pharmacology
- Apoptosis
- Blotting, Western
- Catalysis
- Cell Line
- Cell Line, Tumor
- Chromans -- pharmacology
- Chromatin Immunoprecipitation
- Cloning, Molecular
- Dose-Response Relationship, Drug
- Enzyme Activation
- Gene Expression Regulation, Enzymologic
- Humans
- Ligands
- Mutation
- PPAR gamma -- metabolism
- Plasmids -- metabolism
- Proline Oxidase -- metabolism
- Promoter Regions, Genetic
- Protein Binding
- RNA, Messenger -- metabolism
- Reactive Oxygen Species
- Reverse Transcriptase Polymerase Chain Reaction
- Thiazolidinediones -- pharmacology
- Time Factors
- Troglitazone
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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