Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA(A) alpha5 inverse agonist for cognitive dysfunction. [electronic resource]
Producer: 20060427Description: 872-5 p. digitalISSN:- 0960-894X
- Animals
- Dogs
- Dose-Response Relationship, Drug
- GABA Agonists -- chemical synthesis
- GABA-A Receptor Agonists
- Hydrolysis
- Isoxazoles -- chemical synthesis
- Macaca mulatta
- Mice
- Molecular Conformation
- Protein Subunits -- agonists
- Rats
- Stereoisomerism
- Structure-Activity Relationship
- Tissue Distribution
- Triazines -- chemical synthesis
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Publication Type: Journal Article
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